The Pediatric Choroidal and Ciliary Body Melanoma Study

Prognostic Indicators in Choroidal and Ciliary Body Melanoma

Microcirculation and tumor-infiltrating macrophages in choroidal and ciliary body melanoma and corresponding metastases.

PURPOSE To investigate the relationship between progression to hepatic metastasis and tumor-infiltrating macrophages and microcirculation attributes in uveal melanoma, a cancer that almost invariably disseminates hematogenously to the liver. METHODS A cross-sectional histopathologic analysis of 48 hepatic metastases and corresponding primary choroidal and ciliary body melanomas was conducted,...

Tadalafil-induced subretinal and choroidal hemorrhage in a patient with an unsuspected uveal (choroidal and ciliary body) melanoma.

rhages bilaterally. An old atrophic scar was noted in the left macula, with the right macula appearing normal. There were no vitreal snow balls, snow banking, punched-out chorioretinal scars, nor any other complications. Investigations included a full blood examination and film, calcium levels, syphilis serology, angiotensin-converting enzyme assay, chest radiography, and HLAA29 typing. All res...

Microvascular density in predicting survival of patients with choroidal and ciliary body melanoma.

PURPOSE Although malignant uveal melanoma disseminates predominantly hematogenously because of the absence of intraocular lymphatics, consensus about prognostic impact of microvascular density (MVD) has not been reached. This study was undertaken to investigate whether MVD, microvascular patterns, or both determine prognosis of uveal melanoma. METHODS A population-based retrospective cohort s...

Ciliary body melanoma masquerading as chronic uveitis.

PURPOSE To report a case of ciliary body melanoma that masqueraded as chronic uveitis. METHODS A patient experienced persistent unilateral panuveitis and elevated intraocular pressure. Inflammation and pressure worsened after cataract extraction and lens implantation. Diagnostic vitrectomy was non-revealing. RESULTS Repeat vitrectomy and lens implant removal revealed a ciliary body mass, su...